VThunter

Pangolin

Scientific Name: Manis javanica

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Pholidota-> Manidae-> Manis

Lassa mammarenavirus

Family: Arenaviridae

Receptor: CLEC4G

Receptor CLEC4G information

Summary: This gene encodes a glycan-binding receptor and member of the C-type lectin family which plays a role in the immune response. C-type lectin receptors are pattern recognition receptors located on immune cells that play a role in the recognition and uptake of both self and non-self glycoproteins as well as mediating cell adhesion, glycoprotein clearance, and cell signaling functions. This gene's protein binds complex-type N-glycans of the viral envelope proteins of Ebola virus, West Nile filovirus, and SARS coronavirus, but not HIV or hepatitis C virus. In mouse, this protein has been shown to recognize activated T-cells and to negatively regulate T-cell receptor-mediated signalling. It also acts as a novel, liver-specific regulator of NK cell-mediated immunity in mouse. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2020] [NCBI] [Proteinatlas]

Data Source

Data set information

Project	Date	Technology	Tissue	Condition	Cell	PMID/DOI
Vthunter_0035	2021.04	10X Genomics	Duodenum	Normal	1482	Link
Vthunter_0036	2021.04	10X Genomics	Esophagus	Normal	24581	Link
Vthunter_0037	2021.04	10X Genomics	Heart	Normal	12958	Link
Vthunter_0038	2021.04	10X Genomics	Kidney	Normal	4481	Link
Vthunter_0039	2021.04	10X Genomics	LargeIntestine	Normal	3328	Link
Vthunter_0040	2021.04	10X Genomics	Liver	Normal	5694	Link
Vthunter_0041	2021.04	10X Genomics	Lung	Normal	13720	Link